KOL-validated pathways
Rare disease definitions curated and signed off by key opinion leaders, not free-text guesses, so every cohort is reproducible and defensible.
Rare disease clinical decision support
Transform the diagnostic odyssey into a path of discovery.
PathfindEHR™ helps rare disease clinicians find the undiagnosed and underdiagnosed, revealing the patients hidden in existing health data, and finding clarity amidst complexity.
HIPAA-eligible · KOL-validated disease pathways · Governed & reproducible
The rare disease challenge
Rare disease is anything but rare.
Individually each disease is rare. Together they affect more than 30 million Americans. Yet patients wait years for a diagnosis that is often already hidden in their data. That delay is the problem PathfindEHR™ exists to solve.
- 10,000+
- known rare diseases
- 1 in 10
- Americans affected
- 5+ yrs
- average time to diagnosis
- <5%
- have an approved treatment
How we find them
Figures: NORD. The zebra is the symbol of the rare disease community.
We empower pharmaceutical and diagnostic firms through high-value, sustainable partnerships with clinicians and health systems, accelerating solutions and improving patient outcomes.
Built for the people advancing rare disease care
- Academic medical centers
- Rare disease clinicians
- Research consortia
- Life-science partners
- Specialty networks
The PathfindEHR™ platform
Find the rare disease patients no one else can see.
Rare disease patients endure years and many specialists before a diagnosis. PathfindEHR™ shortens that journey, applying governed disease pathways and AI across the FHIR and real-world data health systems already hold.
AI & machine learning
Models surface subtle signals across years of records that a single chart review would never connect.
Real-world health data
Works on the EHR and real-world data you already have. No new data collection required.
Patient finding
Surface the undiagnosed and underdiagnosed who fit a rare disease profile — a prioritized, explainable list of candidates for specialist review.
Step 1
Define the disease
Key opinion leaders curate a governed disease pathway (codes, signals, inclusions and exclusions), reviewed and signed off by a clinician panel, never improvised.
Step 2
Search the terrain
PathfindEHR™ applies the pathway across existing EHR and real-world data with AI/ML to find patients who match.
Step 3
Reveal the hidden patient
Get an explainable list of candidates, each with its supporting evidence, turning years of scattered data into a clear starting point for clinical review.
KOL-validated. Every disease pathway is curated and signed off by key opinion leaders before it’s ever used.
How we partner
Flexible engagement models around a single governed engine.
Strategic patient-finding programs
Multi-year collaborations where we jointly define disease pathways, run recurring patient-finding on your EHR/RWD, and measure downstream impact on diagnosis, trial enrollment, and therapy uptake.
Learn moreTargeted pilots and proof-of-concept
Narrowly scoped pilots focused on a single disease or franchise, designed to de-risk integration, validate yield and lift, and build the internal case for broader deployment.
Learn moreEmbedded expertise and advisory
Access to our diagnostic strategy team for pathway refinement, trial design support, indication expansion, and evidence-generation planning — with PathfindEHR™ cohorts as the starting point, not the endpoint.
Learn moreOne engine, a product family
One governed engine. A family of products.
PathfindEHR™ is built on a single governed, HIPAA-eligible engine, proven first on the hardest problem in medicine, rare disease. The same core powers a growing family of products, sharing a patient-finding and governed-scoring foundation while serving different needs.
- Available now
PathfindEHR™
Rare disease CDSS
Our live product for rare disease clinicians: governed, KOL-approved condition content plus patient finding to surface the undiagnosed.
- In development
Research Workspace
The research engine
The same governed engine, offered to institutions to run their own research: gather sources, curate evidence, and synthesize, on their own data and topics.
- On the roadmap
Patient Portal
For patients
A patient-facing space to understand a condition and find clinical trials, closing the loop between discovery and care.
Interested in our research workspace or patient portal as they develop? Tell us what you need.
- 50+
- Years of combined experience
- 150
- Tools developed
- 200
- Collaborations worldwide
- 100%
- Top 100 hospitals
Experience you can trust
A guide through the wilderness of complex diagnosis.
Decades of diagnostic experience, focused on the hardest problem in rare disease: finding the patient. It’s why partners and the press take notice.
Someone who can see the path where others only see a thicket of complexity. Raymond Tarr is that kind of guide.
FAQ
Questions, answered.
What is PathfindEHR™?
A HIPAA-eligible clinical decision support system that helps rare disease clinicians surface undiagnosed and underdiagnosed candidates hidden in existing health data, using governed, KOL-validated disease pathways, AI/ML, and real-world clinical data.
Does PathfindEHR™ diagnose patients?
No. PathfindEHR™ is decision support, not a diagnostic device. It surfaces candidate patients and the specific evidence behind each, so a qualified clinician can independently review the basis and make every clinical decision. It does not diagnose and is not a substitute for clinical judgment.
How is patient data kept secure?
PathfindEHR™ analyzes data where it already lives. It reads standard FHIR and real-world data inside your governed environment. No migration and no copying PHI out. The platform is HIPAA-eligible and built to be auditable end to end.
What data do we need to provide?
Standard FHIR and real-world clinical data you already hold. There’s no bespoke data model to build first. The platform works with the records your systems already produce.
How are disease definitions validated?
Every disease pathway is curated and signed off by key opinion leaders (KOLs) before it’s used. Definitions are governed, versioned, and reproducible: the same inputs always produce the same patients, so results are clinically defensible.
Who is PathfindEHR™ for?
Rare disease clinicians, clinical researchers, and the health systems and life-science partners who work with them: anyone who needs to find a hard-to-locate patient population reliably.
How do we get started?
Request a demo. We’ll apply a governed disease pathway to a real cohort and walk you through the path of discovery on your data.
Ready to find the patients hidden in your data?
See PathfindEHR™ applied to a rare disease cohort. We’ll walk you through the path of discovery.